I've got a Shimano RS21 wheel in for service.

It's used for cyclocross apparently.
The wheel wasn't really out of true at all.
The centering was spot-on front and rear.
It was so perfectly centered that if I'd struggled with truing it, I probably would've thrown it out of alignment instead.
Not related to trueness or centering, but
the front wheel was rotating pretty roughly.
Given how long it's been in use, there's no way the bearing races should be pitting yet, so I adjusted the bearing preload and it turned into "zero play with smooth, silky rotation."
If they'd kept using it like that, they would've induced pitting in short order.
Since cup-and-cone hubs have become rare lately,
I don't get many jobs pursuing that perfect bearing adjustment anymore.

One of the advantages of straight-pull spokes is
that "the spokes don't protrude past the hub flange."
Interference between the sprocket or rear derailleur pulley cage and the spokes
basically doesn't happen.
If you leverage this well in the design, you can position the right flange as far outward as possible while still being 11-speed compatible.

This is maximum offset rimming within the range of not using internal-nipple construction.

It's used for cyclocross apparently.
The wheel wasn't really out of true at all.
The centering was spot-on front and rear.
It was so perfectly centered that if I'd struggled with truing it, I probably would've thrown it out of alignment instead.
Not related to trueness or centering, but
the front wheel was rotating pretty roughly.
Given how long it's been in use, there's no way the bearing races should be pitting yet, so I adjusted the bearing preload and it turned into "zero play with smooth, silky rotation."
If they'd kept using it like that, they would've induced pitting in short order.
Since cup-and-cone hubs have become rare lately,
I don't get many jobs pursuing that perfect bearing adjustment anymore.

One of the advantages of straight-pull spokes is
that "the spokes don't protrude past the hub flange."
Interference between the sprocket or rear derailleur pulley cage and the spokes
basically doesn't happen.
If you leverage this well in the design, you can position the right flange as far outward as possible while still being 11-speed compatible.

This is maximum offset rimming within the range of not using internal-nipple construction.